Cenforce 100 (sildenafil citrate) is generally more effective when taken on an empty stomach. Food, especially high-fat meals, can slow down the absorption of the medication, delaying its onset of action. When taken without food, Cenforce usually starts working within 30 to 60 minutes, allowing for more reliable and quicker results. Taking it on a full stomach may reduce its effectiveness or delay its impact. For best results, it’s recommended to take Cenforce on an empty stomach or after a light meal, and always follow your doctor’s instructions for safe use.